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B 12 enhances TNF- and nerve growth factor secretion and reduces the levels of epidermal growth factor and IL-6 [35]

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Similar to NFU1 patients, the OXPHOS profile in cultured skin fibroblasts and skeletal muscle displayed a decreased activity of complexes I and II

It is primarily the stromal cells that produce extracellular matrix and form fibrotic scar tissue

2020;75(Feb):47380
