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Description
Two studies described target site resistance

During the first one to two weeks, many patients begin to notice subtle changes

[17] While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B 12 -deficient anemia as a whole, regardless of cause

E.PandieM.SvenssonE

Thats definitely not the truth in the presence of Accutane, though
