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Complications of vitamin B12 or folate deficiency anaemia Although it's uncommon, vitamin B12 or folate deficiency (with or without anaemia) can lead to complications, particularly if you have been deficient in vitamin B12 or folate for some time

Their release of histamine, tryptase, and matrix metalloproteinases (e.g., MMP9) contributes to blood-brain barrier breakdown and promotes infiltration of autoreactive T cells

doi:10.1016/j.rbmo.2018.09.016

Are B12 shots safe long-term

2008;131(Pt 7):17221735
