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So depression is an inflammatory disease, but where does the inflammation come from

Brydges CR, Bhattacharyya S, Dehkordi SM, Milaneschi Y, Penninx B, Jansen R, et al

Assessing the degree to which cognitive dysfunction is caused by hepatic insufficiency can be challenging, as not only can a multitude of potential concurrent factors such as infection, renal failure, drugs, or pre-existing cognitive/psychiatric disorders contribute to and exacerbate HE, but causes of underlying liver disease such as alcohol [25], obesity [26] and Hepatitis C [27] may also lead to impairment in cognitive ability

Following SARS-CoV-2 infection, memory loss and cognitive failure can develop and lead to long-COVID, also termed long-haul COVID, chronic COVID-19, or post-acute COVID (325, 336, 341345)

Improved attentional performance following citicoline administration in healthy adult women
