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This means they could affect the absorption of vitamin B12, which can potentially lead to vitamin B12 deficiency or worsen it in someone who already has it

Nervenarzt (2006) 77: 1228

Individuals with a personal history of acnewhether during adolescence or adulthoodmay theoretically be more susceptible, as their skin may already have a propensity towards follicular inflammation and altered sebaceous gland activity
