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One of MOTS-C's downstream effects is increasing intracellular NAD+ utilization the mitochondria are running harder, so they're consuming more of the NAD+ pool

So its important to supplement in some way if youre not getting enough vitamin B12 through your diet alone

[7] Also, the WHO recognizes injectable B12 as an essential medicine, especially for conditions where gut absorption is compromised

Some protocols combine growthhormonerelated peptides with appetitemodulating agents to improve satiety, insulin sensitivity, and fat burning while preserving or increasing lean muscle mass when paired with resistance training