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reported symptomatic improvement in a rat model of FM following stem cell therapy [175]

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Using an ex vivo granuloma explant model, this study identified clemastine, an antihistamine drug, to reduce the mycobacterial growth within complex established granulomas through potentiation of the purinergic receptor P2RX7 (42)

While the Warburg effect is a hallmark of cancer metabolism, recent studies have identified other metabolic features, including metabolic symbiosis, glutamine metabolism, and the reverse Warburg effect, wherein CAFs in the tumor stroma cause autophagy and glycolysis to produce lactate (4346)