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The first two clinical trials are currently in the recruitment phase, focusing on evaluating the safety and efficacy of their respective stem cell treatments on distinct sample groups

these bioactive molecules act on multiple targetsincluding EMT-related transcription factors and key signaling cascadesto effectively block epithelial-mesenchymal conversion, suppress myofibroblast activation and regulate aberrant extracellular-matrix (ECM) remodeling, thereby markedly curbing EMT progression and fibrotic disease ( Triptolide (TP), an active diterpenoid extracted from Tripterygium wilfordii Hook F, possesses anti-inflammatory, antiproliferative and immunomodulatory properties, and has been widely investigated in experimental idiopathic pulmonary fibrosis (IPF) models in recent years ( Total saponins of Astragalus membranaceus (ASTs) are the principal active constituents isolated from Astragalus membranaceus

Nevertheless, a molecular understanding of how the infection modulates bacterial compositions in distant organs is urgently needed

Modified enzymes that simultaneously cleave IgM and IgG have been reported to reduce antibody neutralization and complement activation during AAV gene transfer

Post-treatment support: Applied after radiotherapy or surgery for tissue recoverynot during active chemotherapy