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Environ Mol Mutagen 60(3):227242

The endothelial cells are tightly connected by intracellular junctions that play a crucial role in maintaining the highly selective permeability of the BBB, allowing it to regulate the movement of ions, molecules, and cells between the blood and the neural tissue ( This highly selective and regulated nature of the BBB presents a significant challenge in the treatment of GB

PMID: 29955166 Charney DS et al (1981): The clinical use of clonidine in abrupt withdrawal from methadone

Tissue heals faster while neurons protected from surgical stress