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Such procedures require trained personnel, sterile phlebotomy equipment, and dedicated infrastructure, limiting their suitability for frequent or near-patient monitoring [58]

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The results showed that compared to the control group, the XN-treated group resulted in a significant reduction of epidermal stem cells (P63 + ) in the organoid culture and a decrease in hair growth on the back of nude mice after transplantation (Fig

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In contrast to these findings, skeletal muscle-specific TSC1-deficient mice (TSCmKO), which show sustained activation of mTORC1, developed a late-onset myopathy related to impaired autophagy [62]

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