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HUMAN ACL ACL BIOMECHANICS: Humans typically stand with their heels on the ground and their knees relatively straight during weight-bearing activities
doi: 10.1016/0009-8981(94)90243-7

The topical form draws on decades of clinical data in human skin studies

Ko S-H, Jung Y

Human Equivalent Dose Calculations Using standard conversion formulas accounting for body surface area differences between species, a rat oral dose of 0.0045 mg/lb translates to approximately 0.00073 mg/lb in humans, yielding roughly 0.112 mg/day for a 154-pound person
