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Design, setting, and participants: This 2 2 factorial randomized clinical trial was conducted in research clinics at the University of Minnesota and the University of Pittsburgh, Pennsylvania, from November 2018 to May 2023, with follow-up concluding in June 2024

Visvader, J

Third, if your B12 is elevated and you aren't supplementing or if symptoms persist after you've stopped supplementing that's the signal to look deeper

doi: 10.1242/dmm.025833

It was originally identified as a fragment derived from a larger protein found in human gastric juice, which sparked early scientific interest due to its unusual stability and biological activity under experimental conditions