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As a trivalent lanthanide, gadolinium inhibits a variety of MSCs, including Piezo1 channels, TREK-1, and voltage-gated sodium channels (Biagi and Enyeart, 1990

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documented ERK1/2 phosphorylation and downstream transcription factor activation in vascular models ( Drug Design, Development and Therapy , 2015
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Advise females to inform their prescriber of a known or suspected pregnancy
