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IDH1 inhibition decreased the HTML:TML ratio, l-carnitine:TML ratio and acetylcarnitine:TML ratio in this extract without altering acetyl-CoA (Extended Data Fig

The presenting symptoms are predominantly those of spinal cord compression and neurological deficits, which are dependent on tumor location
It glycosylates Rho and Ras GTPases, disrupting host cell signaling

Sandwich ELISA kits that are sold commercially can be used to measure apoB48 (39, 139, 145)

However, it remains uncertain whether the improved clinical outcomes offered by these medications are related to the reduction in TMAO levels
