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Myristoylated proteins reversibly flip between a myristoyl-accessible state, in which the myristoyl group is available for binding to membranes or other proteins, and a myristoyl-inaccessible state, in which the myristoyl group is located in a hydrophobic-binding pocket within the protein

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However, whether these factors are causally related to CAD has been questioned in MR studies [45, 46], and we found no difference by sex in the risk factors