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In the vitamin B12-only group, the TSH level was comparable to control (0.47 0.17)
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5-amino-1MQ showed concentration-dependent inhibition of NNMT in fully differentiated adipocytes that could be fit to a 3-parameter sigmoidal dose-response curve with a calculated EC50=2.3+/1.1 M (permeable NNMT inhibitorFIGS
