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Mendelian randomization with invalid instruments: effect estimation and bias detection through egger regression

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The spectra quality requirement was full width half height linewidth less than 2.5 x standard deviation (SD) above the group mean

But, you are not the only one feeling this violation of expectation (read NYTimes article in post 119)
doi: 10.1007/978-1-4939-2845-3_3 58 BakDWBechtelTJFalcoJAWeerapanaE