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Applying the ARRIVE guidelines to an in vivo database
Microglia activation is usually followed by proliferation and release of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6 [48], while there is strong evidence that this inflammatory state can lead to neuronal death in vitro and in vivo [49, 50]

CraftSWatsonGS.Insulin and neurodegenerative disease: Shared and specific mechanisms

doi: 10.1016/j.molmed.2013.11.007

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