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While hydroxy-CLZ is most abundant at a potential of 400 mV, demethylation occurs more readily at higher potentials (at around 700 mV versus Pd/H2 reference)

The compound's high membrane permeability and metabolic stability make it suitable for both acute and chronic study designs, but researchers should be aware that its effects on NAD+ and methylation metabolism may require time to fully manifest

Daily Use: Gentle formula suitable for all hair types, including color-treated hair

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