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Alternative oxidase (AOX) has an important influence on both ROS and RNS generation by the respiratory chain in mitochondria (Vanlerberghe, 2013)

The proteins with dual functions are marked in Fig

Astrocyte sodium signaling and neuro-metabolic coupling in the brain

Free androgen index (FAI)s relations with oxidative stress and insulin resistance in polycystic ovary syndrome

There was inadequate data to assess response to combination therapy with both agents
