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Furthermore, oncogenic KRAS is associated with numerous metabolic processes, including induced glucose uptake, re-utilization of glutamine metabolism, and increased autophagy and macropinocytosis

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Interestingly, in two small studies, those with metabolic comorbidities treated with a FAE showed improvement in metabolic syndrome-associated biomarkers 27 and in endothelial function

4.2 Targeting oxidative stress and its mediated ferroptosis As described in 2.2 and 2.4, both oxidative stress and ferroptosis are closely related to the weakening of the antioxidant system and the enhancement of the oxidative system in vivo