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Over the past two decades, preclinical research has expanded to investigate BPC-157's potential effects on various tissue types beyond the gastrointestinal system
The apparent lack of a direct effect was noted due to the in vitro environment not mimicking the inherent environment of a tendon in vivo

Many patients experience relief for 6 months or longer after completing their gel injection series

The study by Xu et al

For instance, fibrotic rigidities have been shown to downregulate MMP-9 expression and secretion in hepatic stellate cells involved in liver fibrosis [119]