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Rat amylin analogs with these affinity-enhancing mutations also significantly enhanced potency for calcitonin receptor activation by 5- to 11-fold compared to endogenous rat amylin and a clinical drug pramlintide (Figure 9D and Table 3)

Both do, within their pharmacokinetic constraints

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doi: 10.1007/BF00403175 36 ForbesJCooperM

Hepatology 2020;72:218296
