glutathione levels in schizophrenia Altered serum disulfide acute relapsed are associated with clinical symptoms and response to electroconvulsive therapy | BMC Psychiatry Dysregulated Oxidative Stress Pathways in

Saffron extracts have been reported in multiple clinical trials and reviews to reduce anxiety and depression symptoms and improve mental health, and have demonstrated efficacy comparable to that of currently used antidepressants

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Similarly, Baker and team affirmed that preexisting Toxoplasma gondii infection augments brain damage during TBI pathogenesis by modulating glutamatergic, neurotoxic, and oxidative stress markers, along with significant elevation in the expression of neuroinflammatory mediators [324]

72 Since the antipsychotic drugs were metabolized by CYP2D6 enzymes, individuals with the PM-predicted phenotype might suffer from dose-dependent complications because of increased plasma levels and result in serious toxicity of antipsychotic drugs