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Description
In hepatocytes UC can upon exposure to 7-hydroxylase be converted into the primary bile acids (cholate or chenodeoxycholate) which are effluxed into the biliary system via the bile salt export protein (ABCB11) [39]

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difficile forms produce the toxins that are responsible for tissue damage and clinical disease

In particular, it appears to promote mitochondrial biogenesis, by enhancing the oxidative capacity of muscle fibers and improving energy efficiency during prolonged efforts
The decision to perform a liver biopsy in patients with renal disease should be individualized based on the clinical assessment of the need for therapy and the need to establish the severity of liver disease (III)
