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To evaluate the role of oxidative stress in various diseases, it is necessary to measure markers of ROS

The introduction of evolved ribosomes and four-base codons, UAA incorporation has enabled the incorporation of more than one defined UAA per protein, although increasing the efficiency of incorporation of multiple UAAs is still problematic and more technological developments are needed in order to make it applicable for future therapeutic applications

This event is followed by a sequential accumulation of cellular NO, ROS and lipid peroxides, mitochondrial ROS and lipid peroxides, and ultimately, culminating in ferroptotic cell death

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A., Zhdanov, V