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A peptide therapy might be easier on the body because peptides are shorter chains of amino acids

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Moreover, the current UA elevation therapy exhibits unstable antioxidant properties, individual variability, and even adverse effects, limiting its potential clinical applications

Gut 45, 592594 (1998)

Figure 1 To assess the potential contribution of gut microbiota to thermogenesis independent of the thermogenic role of UCP1 + cells, we compared rectal body temperature in all experimental groups (Ctrl, Ctrl + Abx, DTR + DT, DTR + DT + Abx) during fasting at room temperature (0h) and cold exposure (4h and 6h)