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*Correspondence: Roland Bol, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying antirheumatic drugs for rheumatoid arthritis: abridged Cochrane systematic review and network meta-analysis

Furthermore, among all treatment groups, the BEAGA/ApoE-PDHD@ILD & R848 nanodrug led to the highest up-regulation of tumor necrosis factor- (TNF- ) and interferon- (IFN- ) (Fig