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For example, peroxisomal -oxidation of di- and trihydroxycholestanoic acid leads to the formation of choloyl-CoA and chenodeoxycholoyl-CoA, then converted by the action of bile acil-CoA: amino acid N-acyltransferase into the taurine and glycine conjugates, which are exported out of the peroxisome into the cytosol and then excreted into the biliary ducts by the bile salt export pump [67]

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Also, acetyl-l-carnitine exerts its antioxidant action through the alteration of the expression and oxidative status of a number of proteins involved in mitochondrial function and brain plasticity [23]

Translation at the rough ER generates a single polyprotein of about 3000 amino acids, which is cleaved by viral and cellular proteases into 10 individual functional proteins 3

2020;67 doi: 10.1016/j.tice.2020.101429.101429 [DOI] [PubMed] [Google Scholar] 8.Fathi E., Kholosi Pashutan M., Farahzadi R., Nozad Charoudeh H