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Sildenafil in term and premature infants: a systematic review

Kung L, Roberts RC

Proc Natl Acad Sci U S A 2000

Because the brain and retina of human infants are not fully developed at birth and may be vulnerable to the effects of taurine deprivation, it has been judged prudent to supplement human infant formulas and pediatric feeding solutions with taurine (7, 27)
The levels of interleukin-1 (IL-1), tumor necrosis factor alpha (TNF-), p38 mitogen-activated protein kinases (p38MAPK), acetylcholine esterase, malondialdehyde (MDA), and nuclear factor kappa B (NF-B) were suppressed, while the brain-derived neurotrophic factor (BDNF) and peroxisome proliferator-activated receptor- (PPAR-) contents were elevated in the brain tissues of AD animals
