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Metabolic health and insulin sensitivity NNMT activity climbs in the fat tissue of people with obesity and type 2 diabetes, which is exactly why the enzyme drew interest as a target for metabolic syndrome in the first place

Deeply elucidating molecular anti-aging mechanisms, investigating interactions with other aging-related signaling pathways (such as mTOR, AMPK, etc.), improving the functional network, and providing theoretical support for more efficient anti-aging interventions

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)

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10.3390/nu13072440 76 LeeY