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Molecular mechanisms of ferroptosis and its role in viral pathogenesis

Microsomal triglyceride transfer protein (MTTP) expression, essential for VLDL assembly, is also reduced in NAFLD, often in parallel with downregulation of apolipoprotein B (ApoB)both of which are critical for efficient hepatic lipid export

Complementing this, cell-based therapies, particularly the transplantation of stem cell-derived retinal pigment epithelium (RPE), aim to address the underlying cellular dysfunction in diseases like AMD, offering the potential to stabilize and perhaps restore retinal structure (Sakai et al., 2025)

[DOI] [PubMed] [Google Scholar] 30.Reuter S.E., Evans A.M

Although most studies on hiPSC-derived SZ neurons studies about SZ have used 2-dimensional (2D) neuronal cultures, technical advances have lately allowed for generation of hiPSC-derived 3-dimensional (3D) brain organoids, which display self-organising capacities mimicking the anatomical structures of the early human fetal cortex [73]