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10.1186/s12891-023-07003-7 94 WangY

The peptide's mobilization of stem cell populationsincluding dermal stem cells and endothelial progenitor cellssupports tissue renewal through recruitment of fresh cellular populations capable of robust synthetic activity

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MITF positively regulates pigmentation-associated genes to promote differentiation-associated function and directly transactivates promoters of three primary melanogenesis enzymes, tyrosinase (TYR), tyrosine-related protein-1 (TYRP-1), and dopachrome tautomerase, also known as tyrosine-related protein-2, TYRP-2 (-2) 55

In the synthesis of BH4, GTP cyclohydrolase 1 (GCH1) serves as the key regulatory enzyme, thereby determining the level of BH4 ( Figure 1 )
