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Mechanisms of acute coronary syndromes and their implications for therapy

& Ansara, I

Results from these multi-scale approaches reveal that cysteines 8 and 83 are the main targets of glutathionylation and oxidation that lead to loss of activity, while cysteine 79 is less vulnerable to oxidation

10.1016/j.molcel.2009.10.012 12 ChhunchhaB.KuboE.SinghD

For cells treated with the RT-AM, real-time ratiometric images of the rapid changes of intracellular GSH concentrations in single cells can be generated by dividing the fluorescence intensity values for the 405 nm channel by the 488 nm channel at each corresponding pixel [1]