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In the POLLUX clinical trial, patients with relapsed or refractory multiple myeloma who received the combination of the anti-CD38 antibody daratumumab with lenalidomide and dexamethasone had significantly prolonged progression-free survival (PFS) relative to those who received lenalidomide and dexamethasone alone

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Recently, many leading regulatory agencies and professional and collegiate sports leagues in the United States have banned its use either by name or by association as a peptide hormone (Table 1)