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Another study showed that chronic social stress, which is a major risk factor for depression, precipitated immune activation in the periphery and dopaminergic regions of the CNS, and reduced dopamine-dependent reward-directed behavior

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doi: 10.3389/fnins.2020.00513 Received 25 February 2020 Accepted 24 April 2020 Published 21 May 2020 Volume 14 - 2020 Edited by Monique Stins, Johns Hopkins University, United States Reviewed by Shilpa Jagdeep Buch, University of Nebraska Medical Center, United States