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Electron micrograph of control rat brain showing normal myelinated nerve with external (e) and internal (i) mesa axons as well as mitochondria (Mi) and vesicles (Ve) present inside the axon (6300)
PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma

doi: 10.1126/scitranslmed.3002629 71 FernandesGFriendPYunisEJGoodRA
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Bendheim PE, Poeggeler B, Neria E, et al