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Description
M2 macrophages possess a weak antigen-presenting ability, and secrete anti-inflammatory cytokines such as IL-10 or TGF-, and down-regulate the immune response [88,89,90].Tumor-associated macrophages (TAMs) have been shown to be functionally plastic as a special type of macrophage, which are often described as M2-like population, but there is also evidence for the existence of M1-like population [91,92,93].In fact, in the early phase of tumor establishment, TAMs display an inflammatory phenotype, but an immunosuppressive phenotype is present at the later stages of tumor progression [94]

Concern was raised that this measure could be potentially harmful to those with vitamin B-12 deficiency caused by the expected increase in folic acid intake (1417)

Chen P, Zhong X, Song Y, et al

Unlike some animal proteins that may trigger inflammation in sensitive individuals, plant-based options provide gentle yet effective anti-inflammatory support

Curr Biol (2021) 31:16531665.E5
