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When the peptide activates or modulates these receptors, it triggers intracellular signaling involving cAMP elevation, protein kinase A activation, and hormone-sensitive lipase stimulation, ultimately leading to triglyceride breakdown and fat mobilization

DSIP and Pain Management In clinical studies, DSIP administration resulted in a notable reduction in pain levels among patients with various pain syndromes, including migraines, vasomotor headaches, chronic tinnitus, and psychogenic pain attacks 6