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However, Cu + is unstable and easily oxidized to Cu 2+ due to the low redox potential of Cu 2+ /Cu +

TRPC6 actively participates in phototransduction in intrinsically photosensitive RGCs (ipRGCs), but C3 and C7 may have a role in the response mechanism of ipRGCs, a small group of ganglion cells that contain melanopsin and respond to light with depolarization and Ca 2+ influx (Berson, 2007

The efficacy of cereblon-based PROTACs also depends on the expression of other proteins that are directly or indirectly involved in the ubiquitination of the POI, such as the DDB1 and CUL4 proteins

Carpenter, A

(Image from Ho et al ., 1998