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To determine acivicin toxicity normal human dermal fibroblasts were treated with a range of concentrations of acivicin for 24 or 48 h and apoptosis was measured by Caspase-Glo 3/7 Assay System (Promega)

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Genes that are involved in lipid accumulation are negatively regulated by Nrf2 [87], and this finding supports the relevance of Nrf2 in NAFLD patients

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[DOI] [PubMed] [Google Scholar] 77.Younossi Z., Stepanova M., Ong J.P., Jacobson I.M., Bugianesi E., Duseja A., Eguchi Y., Wong V.W., Negro F., Yilmaz Y., et al