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Parajuli, B., Horiuchi, H., Mizuno, T., Takeuchi, H

High-Risk Profiles The threshold for testing should be lower if the individual falls into any of these categories: Age 60 or older Long-term use of metformin or proton pump inhibitors (PPIs) Strict vegetarian or vegan diet Family history of pernicious anemia or autoimmune disease Key Clinical Symptoms Neurological and cognitive: tingling, numbness, or a "pins and needles" sensation in the hands or feet

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Bertisch S.M., Sillau S., de Boer I.H., Szklo M., Redline S

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