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Cytosolic Cys experiences the greatest decrease after a single exposure, which is indicative of the model facilitating rapid GSH re-synthesis after an initial depletion

Chen, Talanta 194 , 554 (2019)

In some embodiments, the otic formulation or composition comprises about 15% by weight of the povidone

This increased lipid uptake leads to increased lipid peroxidation, p38 signaling and ferroptosis, effects that can be reversed by overexpression of glutathione peroxidase 4 leading to improved TIL survival and function 186, 187

F374, Dojindo, Japan) was used based on the manufacturers protocol
