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This is called Cerebral Folate Deficiency (CFD) and it happens when there is low folate (vitamin B9) in the brain but normal folate levels in the blood

The Reality: DSIP Is Not an Approved Treatment DSIP is: Not FDA approved Not prescribed in addiction treatment programs Not included in clinical guidelines for opioid use disorder Even though it sounds promising on the surface, theres no strong evidence showing that DSIP can: Reduce cravings Prevent relapse Replace evidence-based treatments Its being discussed far more in online communities and experimental spaces than in real medical settings

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[DOI] [PMC free article] [PubMed] [Google Scholar] 238.Balakrishnan, K

[DOI] [PubMed] [Google Scholar] Andres 2004 Andres E, Loukili NH, Noel E, Kaltenbach G, Ben Abdelgheni M, Perrin AE, et al