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The net effect: BPC-157 creates the physical conditions that make healing possible

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It has been reported that caspase-9 and caspase-3 expression was elevated in both HEI-OC1 cells and cochlear exposed to aminoglycosides, and the use of caspase-9 specific inhibitor (z-LEHD-FMK) or general caspase inhibitor (z-VAD-FMK) was found to effectively reduce the expression of caspase and prevent HC death (Matsui et al., 2003

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