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Conserved role of the linker -helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB

Karonudib is a promising anticancer therapy in hepatocellular carcinoma

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The elevated GSH level helps to prevent apoptosis of cancer cells by detoxifying reactive oxygen species (ROS) [3] and induce chemotherapeutic drugs resistance through GSH spontaneous reactions or xenobiotics reactions catalyzed by GSH S-transferase (GST) [4, 5]
