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Glycyrrhizic acid alleviates gefitinib-induced liver injury by regulating the p53/p21 pathway and releasing cell cycle arrest
Among non-nucleoside DNMT-inhibitors, Procainamide and its ester analog procaine are two FDA-approved drugs respectively used as anti-arrhythmic drugs and local anesthetics, which directly bind DNA and induce a decrease in DNA methylation levels in some cancers (Moreira-Silva et al., 2020)
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