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Further, glutathione oxidation occurs not only chemically but is also catalyzed by enzymes able to use GSH to reduce H 2 O 2 or other peroxides to water or the corresponding alcohol (see section 7.1)

Severe COVID-19 induces extensive pulmonary inflammation, triggering a macrophage activation syndrome (MAS)-like event with proinflammatory cytokines, macrophage and lymphocyte recruitment, and subsequent endothelial damage [15]

4 , nzz102 (2019)

Restoration of glutathione levels in the mycotoxin exposed mouse dendritic cells using NAC or glutathione ethyl ester restored IL-12 secretion and prevented the mycotoxin-induced increase of airway inflammation and airway hyperreactivity [90]

Eryptosis, analogous to apoptosis in nucleated cells, is a physiological process that eliminates senescent or defective erythrocytes before hemolysis occurs, thereby preventing toxicity resulting from the release of hemoglobin into the bloodstream