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This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)

Genes Dev 20:29132921

Key Benefits of Vitamin B12

The choice between cyanocobalamin and hydroxocobalamin might also depend on the neurological symptoms

Documenting this exact ratio is vital for ensuring consistency across your laboratory calculations and replicating your data sets accurately