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One possible hypothesis is based on the ability of the SARS-CoV-2 virus to cross the blood-brain barrier and reach the brain, or that the virus may reach the brain via the hematogenous route 11

Notably, EV-associated DAMPs have been found in stored red blood concentrates [238], suggesting that eryptosis-mediated generation of EVs might exert immunomodulatory DAMP-triggered effects

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New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production

27 , 20632074.e5 (2019)